Antibacterial Properties of Ozonated Sunflower (Helianthus Annuus l.) and Sesame (Sesamum Indicum L.) Oils on Staphylococcus Aureus

Background and Aims: Staphylococcus aureus infection needs long-term treatment with antibiotics which may cause adverse effects on many body organs and antibiotics resistance. Therefore, the use of natural and herbal compounds has been under consideration. Materials and Methods: In the present study, the effects of sunflower (Helianthus annuus) and sesame (Sesamum indicum) oils were assessed on S. aureus growth regarding zone of inhibited growth (Antibiogram test), Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). Results & Discussion: considering antibiogram test, there was a statistically significant difference between sesame and sunflower oil (72 hours ozonate) and pure sesame and sunflower oils and ciprofloxacin antibiotic, as well as negative control distilled water after 24 and 48 hours (P≤0.05). The results showed that antibiotic, ozonated water, ozonated sesame and sunflower oils had 12, 8, 4, and 3 mm inhibition zones after 24 hours on S. aureus bacteria, respectively. The MBC and MIC values of ozonated sunflower and sesame oil on S. aureus were 0.064, 0.022, 0.032 and 0.028 mg/mL, respectively. Sesame and sunflower oils can be used as inhibitors of the growth of S. aureus in pharmaceutical formulations such as wound and burn healing ointments.